Chad M. Walesky, PhD, Receives the ASIP 2017 Young Scientist Leadership Award

waleskyChad M. Walesky, PhD, is an early career scientist leading the way in determining the complex pathology of liver cancer (Cholangiocarcinoma). Walesky is currently a research fellow at Brigham & Women’s Hospital/Harvard Medical School and uses zebra fish as an experimental model to study the disease. Specifically Walesky studies a transcription factor called HNF4α, which binds DNA and can alter the genetic coding of proteins. Targeting HNF4α is clinically relevant as its expression is increased within many different types of cancer. However, due to the complexity of cancer disease progression, focusing on HNF4α alone provides limited insight on understanding Cholangiocarcinoma. Therefore, Walesky studies HNF4α’s interactions with other molecular targets involved in liver cancer to aid in the discovery of novel therapeutics for treatment.

Author: Bryan A. Wilson, Ph.D., M.B.A. – Research Fellow (UNC Chapel Hill School of Medicine)

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